CMOS TIME-RESOLVED, CONTACT, AND MULTISPECTRAL FLUORESCENCE IMAGING FOR DNA MOLECULAR DIAGNOSTICS

CMOS Time-Resolved, Contact, and Multispectral Fluorescence Imaging for DNA Molecular Diagnostics

CMOS Time-Resolved, Contact, and Multispectral Fluorescence Imaging for DNA Molecular Diagnostics

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Instrumental USB Port Connector limitations such as bulkiness and high cost prevent the fluorescence technique from becoming ubiquitous for point-of-care deoxyribonucleic acid (DNA) detection and other in-field molecular diagnostics applications.The complimentary metal-oxide-semiconductor (CMOS) technology, as benefited from process scaling, provides several advanced capabilities such as high integration density, high-resolution signal processing, and low power consumption, enabling sensitive, integrated, and low-cost fluorescence analytical platforms.In this paper, CMOS time-resolved, contact, Pitchers and multispectral imaging are reviewed.

Recently reported CMOS fluorescence analysis microsystem prototypes are surveyed to highlight the present state of the art.

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